Rar Beta Mediated Apoptosis in Breast Cancer Cells

Seewaldt, Victoria L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08CA068210-02
• Application #: 2112093
• Study Section: Cancer Research Manpower and Education Review Committee (CRME)
• Project Start: 1995-09-22
• Project End: 2000-08-31
• Budget Start: 1996-09-01
• Budget End: 1997-08-31
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: University of Washington
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 135646524
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98195

Publications

Dietze, E C; Yee, L; Seewaldt, V L (2001) Suppression of pRB expression in normal human mammary epithelial cells is associated with resistance to all-trans-retinoic acid but not N-(4-hydroxylphenyl)-retinamide. Breast Cancer Res Treat 66:41-50

Seewaldt, V L; Kim, J H; Parker, M B et al. (1999) Dysregulated expression of cyclin D1 in normal human mammary epithelial cells inhibits all-trans-retinoic acid-mediated G0/G1-phase arrest and differentiation in vitro. Exp Cell Res 249:70-85

Seewaldt, V L; Dietze, E C; Johnson, B S et al. (1999) Retinoic acid-mediated G1-S-phase arrest of normal human mammary epithelial cells is independent of the level of p53 protein expression. Cell Growth Differ 10:49-59

Seewaldt, V L; Caldwell, L E; Johnson, B S et al. (1997) Inhibition of retinoic acid receptor function in normal human mammary epithelial cells results in increased cellular proliferation and inhibits the formation of a polarized epithelium in vitro. Exp Cell Res 236:16-28

Seewaldt, V L; Kim, J H; Caldwell, L E et al. (1997) All-trans-retinoic acid mediates G1 arrest but not apoptosis of normal human mammary epithelial cells. Cell Growth Differ 8:631-41