Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08CA071429-01
Application #
2115057
Study Section
Cancer Research Manpower and Education Review Committee (CRME)
Project Start
1996-09-01
Project End
2001-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Grall, Franck T; Prall, Wolf C; Wei, Wanjiang et al. (2005) The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes. FEBS J 272:1676-87
Grall, Franck; Gu, Xuesong; Tan, Lujian et al. (2003) Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1. Arthritis Rheum 48:1249-60
Dube, A; Thai, S; Gaspar, J et al. (2001) Elf-1 is a transcriptional regulator of the Tie2 gene during vascular development. Circ Res 88:237-44
Rudders, S; Gaspar, J; Madore, R et al. (2001) ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kappa B to regulate the inducible nitric-oxide synthase gene. J Biol Chem 276:3302-9
Oettgen, P; Finger, E; Sun, Z et al. (2000) PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J Biol Chem 275:1216-25
Kas, K; Finger, E; Grall, F et al. (2000) ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1. J Biol Chem 275:2986-98
Oettgen, P; Kas, K; Dube, A et al. (1999) Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes. J Biol Chem 274:29439-52
Dube, A; Akbarali, Y; Sato, T N et al. (1999) Role of the Ets transcription factors in the regulation of the vascular-specific Tie2 gene. Circ Res 84:1177-85
Oettgen, P; Barcinski, M; Boltax, J et al. (1999) Genomic organization of the human ELF3 (ESE-1/ESX) gene, a member of the Ets transcription factor family, and identification of a functional promoter. Genomics 55:358-62
Iljin, K; Dube, A; Kontusaari, S et al. (1999) Role of ets factors in the activity and endothelial cell specificity of the mouse Tie gene promoter. FASEB J 13:377-86

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