Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08DK001899-03
Application #
3080767
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1988-09-30
Project End
1993-08-31
Budget Start
1990-09-01
Budget End
1991-08-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Veronikis, I E; Alex, S; Fang, S L et al. (1996) Serum iodothyronine concentrations in intestinally decontaminated rats treated with a 5'-deiodinase type I inhibitor 6-anilino-2-thiouracil. Eur J Endocrinol 134:519-23
Turka, L A; Gratiot-Deans, J; Keim, D et al. (1993) Elevated proliferating cell nuclear antigen levels in immature thymocytes. Dissociation from cell cycle progression. J Immunol 150:2746-52
Gratiot-Deans, J; Ding, L; Turka, L A et al. (1993) bcl-2 proto-oncogene expression during human T cell development. Evidence for biphasic regulation. J Immunol 151:83-91
Turka, L A; Linsley, P S; Lin, H et al. (1992) T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc Natl Acad Sci U S A 89:11102-5
Gratiot-Deans, J; Keim, D; Strahler, J R et al. (1992) Differential expression of Op18 phosphoprotein during human thymocyte maturation. J Clin Invest 90:1576-81
Paine 3rd, R; Chavis, A; Gaposchkin, D et al. (1992) A factor secreted by a human pulmonary alveolar epithelial-like cell line blocks T-cell proliferation between G1 and S phase. Am J Respir Cell Mol Biol 6:658-66
Turka, L A; Linsley, P S; Paine 3rd, R et al. (1991) Signal transduction via CD4, CD8, and CD28 in mature and immature thymocytes. Implications for thymic selection. J Immunol 146:1428-36
Turka, L A; Dayton, J; Sinclair, G et al. (1991) Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine. J Clin Invest 87:940-8
Paine 3rd, R; Mody, C H; Chavis, A et al. (1991) Alveolar epithelial cells block lymphocyte proliferation in vitro without inhibiting activation. Am J Respir Cell Mol Biol 5:221-9
Turka, L A; Schatz, D G; Oettinger, M A et al. (1991) Thymocyte expression of RAG-1 and RAG-2: termination by T cell receptor cross-linking. Science 253:778-81

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