Thyrotropin-Alpha Subunit Gene Transcription Factors

Sarapura, Virginia D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08DK002169-04
• Application #: 2133943
• Study Section: Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
• Project Start: 1993-01-01
• Project End: 1997-12-31
• Budget Start: 1996-01-19
• Budget End: 1996-12-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Colorado Denver
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 065391526
• City: Aurora
• State: CO
• Country: United States
• Zip Code: 80045

Publications

Sarapura, Virginia D; Wood, William M; Woodmansee, Whitney W et al. (2006) Pituitary tumors arising from glycoprotein hormone alpha-subunit-deficient mice contain transcription factors and receptors present in thyrotropes. Pituitary 9:11-8

Sarapura, V D; Strouth, H L; Wood, W M et al. (1998) Activation of the glycoprotein hormone alpha-subunit gene promoter in thyrotropes. Mol Cell Endocrinol 146:77-86

Sarapura, V D; Wood, W M; Bright, T M et al. (1997) Reconstitution of triiodothyronine inhibition in non-triiodothyronine-responsive thyrotropic tumor cells using transfected thyroid hormone receptor isoforms. Thyroid 7:453-61

Sarapura, V D; Strouth, H L; Gordon, D F et al. (1997) Msx1 is present in thyrotropic cells and binds to a consensus site on the glycoprotein hormone alpha-subunit promoter. Mol Endocrinol 11:1782-94

James, R A; Sarapura, V D; Bruns, C et al. (1997) Thyroid hormone-induced expression of specific somatostatin receptor subtypes correlates with involution of the TtT-97 murine thyrotrope tumor. Endocrinology 138:719-24