Molecular Mechanisms of Thyroid Hormone Action

Yen, Paul M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08DK002186-03
• Application #: 2133974
• Study Section: Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
• Project Start: 1994-01-01
• Project End: 1997-08-31
• Budget Start: 1996-01-25
• Budget End: 1997-08-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Brigham and Women's Hospital
• DUNS #: 071723621
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02115

Publications

Yen, P M; Liu, Y; Sugawara, A et al. (1996) Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity. J Biol Chem 271:10910-6

Yen, P M; Wilcox, E C; Hayashi, Y et al. (1995) Studies on the repression of basal transcription (silencing) by artificial and natural human thyroid hormone receptor-beta mutants. Endocrinology 136:2845-51

Yen, P M; Sugawara, A; Liu, Y et al. (1995) Factors that enhance Escherichia coli-expressed TR beta binding to T3 and DNA. Thyroid 5:309-13

Yen, P M; Chin, W W (1994) Molecular mechanisms of dominant negative activity by nuclear hormone receptors. Mol Endocrinol 8:1450-4