Hepatitis C Virus-Specific Replicase

Chung, Raymond T.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08DK002209-03
• Application #: 2134011
• Study Section: Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
• Project Start: 1994-01-10
• Project End: 1998-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Massachusetts General Hospital
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02199

Publications

Chung, R T; He, W; Saquib, A et al. (2001) Hepatitis C virus replication is directly inhibited by IFN-alpha in a full-length binary expression system. Proc Natl Acad Sci U S A 98:9847-52

Chung, R T; Kaplan, L M (1999) Heterogeneous nuclear ribonucleoprotein I (hnRNP-I/PTB) selectively binds the conserved 3' terminus of hepatitis C viral RNA. Biochem Biophys Res Commun 254:351-62

Chung, R T; Monto, A; Dienstag, J L et al. (1999) Mutations in the NS5A region do not predict interferon-responsiveness in american patients infected with genotype 1b hepatitis C virus. J Med Virol 58:353-8

Baid, S; Pascual, M; Williams Jr, W W et al. (1999) Renal thrombotic microangiopathy associated with anticardiolipin antibodies in hepatitis C-positive renal allograft recipients. J Am Soc Nephrol 10:146-53

Toth, C M; Pascual, M; Chung, R T et al. (1998) Hepatitis C virus-associated fibrosing cholestatic hepatitis after renal transplantation: response to interferon-alpha therapy. Transplantation 66:1254-8

Pascual, M; Thadhani, R; Chung, R T et al. (1997) Nephrotic syndrome after liver transplantation in a patient with hepatitis C virus-associated glomerulonephritis. Transplantation 64:1073-6