Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08DK002417-01
Application #
2134364
Study Section
Special Emphasis Panel (SRC)
Project Start
1996-04-15
Project End
2001-03-31
Budget Start
1996-04-15
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Rafiee, Parvaneh; Ogawa, Hitoshi; Heidemann, Jan et al. (2003) Isolation and characterization of human esophageal microvascular endothelial cells: mechanisms of inflammatory activation. Am J Physiol Gastrointest Liver Physiol 285:G1277-92
Rafiee, Parvaneh; Johnson, Christopher P; Li, Mona S et al. (2002) Cyclosporine A enhances leukocyte binding by human intestinal microvascular endothelial cells through inhibition of p38 MAPK and iNOS. Paradoxical proinflammatory effect on the microvascular endothelium. J Biol Chem 277:35605-15
Chai, Yuh-Cherng; Binion, David G; Macklis, Roger et al. (2002) Smooth muscle cell proliferation induced by oxidized LDL-borne lysophosphatidylcholine. Evidence for FGF-2 release from cells not extracellular matrix. Vascul Pharmacol 38:229-37
Binion, D G; Rafiee, P; Ramanujam, K S et al. (2000) Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion. Free Radic Biol Med 29:881-8
Binion, D G; Fu, S; Ramanujam, K S et al. (1998) iNOS expression in human intestinal microvascular endothelial cells inhibits leukocyte adhesion. Am J Physiol 275:G592-603
Binion, D G; West, G A; Volk, E E et al. (1998) Acquired increase in leucocyte binding by intestinal microvascular endothelium in inflammatory bowel disease. Lancet 352:1742-6
Binion, D G; West, G A; Ina, K et al. (1997) Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease. Gastroenterology 112:1895-907