Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08HD000977-05
Application #
2194460
Study Section
Population Research Committee (HDPR)
Project Start
1992-05-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Wang, Liqin; Feng, Ying-Hong; Gorodeski, George I (2005) Epidermal growth factor facilitates epinephrine inhibition of P2X7-receptor-mediated pore formation and apoptosis: a novel signaling network. Endocrinology 146:164-74
Gorodeski, George I (2004) Estrogen attenuates P2X7-R-mediated apoptosis of uterine cervical cells by blocking calcium influx. Nucleosides Nucleotides Nucleic Acids 23:1287-93
Gorodeski, George I; Haens, Geert (2003) Nitric oxide regulation of permeability in human cervical and vaginal epithelial cells and in human endothelial cells. Curr Pharm Des 9:411-8
Gorodeski, George I (2002) Regulation of transcervical permeability by two distinct P2 purinergic receptor mechanisms. Am J Physiol Cell Physiol 282:C75-83
Gorodeski, George I (2002) Expression, regulation, and function of P2X(4) purinergic receptor in human cervical epithelial cells. Am J Physiol Cell Physiol 282:C84-93
Gorodeski, G I (2001) Estrogen biphasic regulation of paracellular permeability of cultured human vaginal-cervical epithelia. J Clin Endocrinol Metab 86:4233-43
Gorodeski, G I (2000) NO increases permeability of cultured human cervical epithelia by cGMP-mediated increase in G-actin. Am J Physiol Cell Physiol 278:C942-52
Gorodeski, G I (2000) cGMP-dependent ADP depolymerization of actin mediates estrogen increase in cervical epithelial permeability. Am J Physiol Cell Physiol 279:C2028-36
Gorodeski, G I (2000) Effects of menopause and estrogen on cervical epithelial permeability. J Clin Endocrinol Metab 85:2584-95
Gorodeski, G I; Pal, D (2000) Involvement of estrogen receptors alpha and beta in the regulation of cervical permeability. Am J Physiol Cell Physiol 278:C689-96

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