Somatic Cell Genetics Approach to Muscle Development

Horwitz, Marshall S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08HD001080-03
• Application #: 2194665
• Study Section: Maternal and Child Health Research Committee (HDMC)
• Project Start: 1995-01-01
• Project End: 1998-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Washington
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 135646524
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98195

Publications

Coonrod, A; Li, F Q; Horwitz, M (1997) On the mechanism of DNA transfection: efficient gene transfer without viruses. Gene Ther 4:1313-21

Horwitz, M (1996) Hypermethylated myoblasts specifically deficient in MyoD autoactivation as a consequence of instability of MyoD. Exp Cell Res 226:170-82

Li, F Q; Coonrod, A; Horwitz, M (1996) Preferential MyoD homodimer formation demonstrated by a general method of dominant negative mutation employing fusion with a lysosomal protease. J Cell Biol 135:1043-57

Gogos, J A; Thompson, R; Lowry, W et al. (1996) Gene trapping in differentiating cell lines: regulation of the lysosomal protease cathepsin B in skeletal myoblast growth and fusion. J Cell Biol 134:837-47