Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08HL002721-05
Application #
2210444
Study Section
Special Emphasis Panel (SRC (FB))
Project Start
1992-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Pediatrics
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Onyia, J E; Clapp, D W; Long, H et al. (1998) Osteoprogenitor cells as targets for ex vivo gene transfer. J Bone Miner Res 13:20-30
Bernstein, J; Boyle, D W; Srour, E F et al. (1997) Variation in long-term engraftment of a large consecutive series of lambs transplanted in utero with human hematopoietic cells. Biol Blood Marrow Transplant 3:247-54
Freie, B W; Dutt, P; Clapp, D W (1996) Correction of Fanconi anemia type C phenotypic abnormalities using a clinically suitable retroviral vector infection protocol. Cell Transplant 5:385-93
Haneline, L S; Marshall, K P; Clapp, D W (1996) The highest concentration of primitive hematopoietic progenitor cells in cord blood is found in extremely premature infants. Pediatr Res 39:820-5
Bollag, G; Clapp, D W; Shih, S et al. (1996) Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells. Nat Genet 12:144-8
Clapp, D W; Freie, B; Lee, W H et al. (1995) Molecular evidence that in situ-transduced fetal liver hematopoietic stem/progenitor cells give rise to medullary hematopoiesis in adult rats. Blood 86:2113-22
Clapp, D W; Williams, D A (1995) The use of umbilical cord blood as a cellular source for correction of genetic diseases affecting the hematopoietic system. Stem Cells 13:613-21
Traycoff, C M; Abboud, M R; Laver, J et al. (1994) Rapid exit from G0/G1 phases of cell cycle in response to stem cell factor confers on umbilical cord blood CD34+ cells an enhanced ex vivo expansion potential. Exp Hematol 22:1264-72