Upregulation of 5-Lipoxygenase in Alveolar Macrophages

Coffey, Michael J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08HL002810-05
• Application #: 2210605
• Study Section: Research Training Review Committee (RTR)
• Project Start: 1992-07-01
• Project End: 1997-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: University of Michigan Ann Arbor
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 791277940
• City: Ann Arbor
• State: MI
• Country: United States
• Zip Code: 48109

Publications

Coffey, M J; Phare, S M; George, S et al. (1998) Granulocyte colony-stimulating factor administration to HIV-infected subjects augments reduced leukotriene synthesis and anticryptococcal activity in neutrophils. J Clin Invest 102:663-70

Coffey, M J; Woffendin, C; Phare, S M et al. (1997) RANTES inhibits HIV-1 replication in human peripheral blood monocytes and alveolar macrophages. Am J Physiol 272:L1025-9

Woods, J W; Coffey, M J; Brock, T G et al. (1995) 5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation. J Clin Invest 95:2035-46