Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08HL003498-01
Application #
2211762
Study Section
Special Emphasis Panel (ZHL1-CSR-Y (F1))
Project Start
1996-07-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Drachman, Jonathan G; Miyakawa, Yoshitaka; Luthi, Jennifer N et al. (2002) Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation. J Biol Chem 277:23544-53
Martin-Soudant, N; Drachman, J G; Kaushansky, K et al. (2000) CDP/Cut DNA binding activity is down-modulated in granulocytes, macrophages and erythrocytes but remains elevated in differentiating megakaryocytes. Leukemia 14:863-73
Rojnuckarin, P; Drachman, J G; Kaushansky, K (1999) Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: role in endomitosis. Blood 94:1273-82
Drachman, J G; Millett, K M; Kaushansky, K (1999) Thrombopoietin signal transduction requires functional JAK2, not TYK2. J Biol Chem 274:13480-4
Drachman, J G; Kaushansky, K (1997) Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain. Proc Natl Acad Sci U S A 94:2350-5