Volatile Anesthetics and Ion Channel Modulation

Pearce, Robert A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08NS001548-05
• Application #: 2259463
• Study Section: NST-2 Subcommittee (NST)
• Program Officer: Kitt, Cheryl A
• Project Start: 1991-12-01
• Project End: 1996-11-30
• Budget Start: 1995-12-01
• Budget End: 1996-11-30
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: University of Wisconsin Madison
• Department: Anesthesiology
• Type: Schools of Medicine
• DUNS #: 161202122
• City: Madison
• State: WI
• Country: United States
• Zip Code: 53715

Publications

Banks, M I; Li, T B; Pearce, R A (1998) The synaptic basis of GABAA,slow. J Neurosci 18:1305-17

Pearce, R A (1996) Volatile anaesthetic enhancement of paired-pulse depression investigated in the rat hippocampus in vitro. J Physiol 492 ( Pt 3):823-40

Pearce, R A; Grunder, S D; Faucher, L D (1995) Different mechanisms for use-dependent depression of two GABAA-mediated IPSCs in rat hippocampus. J Physiol 484 ( Pt 2):425-35

Pearce, R A (1993) Physiological evidence for two distinct GABAA responses in rat hippocampus. Neuron 10:189-200

Banks, M I; Pearce, R A; Smith, P H (1993) Hyperpolarization-activated cation current (Ih) in neurons of the medial nucleus of the trapezoid body: voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in the auditory brain stem. J Neurophysiol 70:1420-32