Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08NS001741-03
Application #
2259878
Study Section
NST-2 Subcommittee (NST)
Project Start
1994-07-01
Project End
1999-04-30
Budget Start
1996-07-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Neurology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Schaack, J; Allen, B; Orlicky, D J et al. (2001) Promoter strength in adenovirus transducing vectors: down-regulation of the adenovirus E1A promoter in 293 cells facilitates vector construction. Virology 291:101-9
Smith, R L; Morroni, J; Wilcox, C L (2001) Lack of effect of treatment with penciclovir or acyclovir on the establishment of latent HSV-1 in primary sensory neurons in culture. Antiviral Res 52:19-24
Smith, R L; Traul, D L; Schaack, J et al. (2000) Characterization of promoter function and cell-type-specific expression from viral vectors in the nervous system. J Virol 74:11254-61
Moorhead, J W; Clayton, G H; Smith, R L et al. (1999) A replication-incompetent adenovirus vector with the preterminal protein gene deleted efficiently transduces mouse ears. J Virol 73:1046-53
Clayton, G H; Perez, G M; Smith, R L et al. (1998) Expression of mRNA for the elav-like neural-specific RNA binding protein, HuD, during nervous system development. Brain Res Dev Brain Res 109:271-80
Oberhaus, S M; Smith, R L; Clayton, G H et al. (1997) Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis. J Virol 71:2100-6
Wilcox, C L; Smith, R L; Everett, R D et al. (1997) The herpes simplex virus type 1 immediate-early protein ICP0 is necessary for the efficient establishment of latent infection. J Virol 71:6777-85
Smith, R L; Geller, A I; Escudero, K W et al. (1995) Long-term expression in sensory neurons in tissue culture from herpes simplex virus type 1 (HSV-1) promoters in an HSV-1-derived vector. J Virol 69:4593-9
Smith, R L; Clayton, G H; Wilcox, C L et al. (1995) Differential expression of an inwardly rectifying chloride conductance in rat brain neurons: a potential mechanism for cell-specific modulation of postsynaptic inhibition. J Neurosci 15:4057-67