Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08NS001857-01A1
Application #
2260073
Study Section
NST-2 Subcommittee (NST)
Project Start
1996-09-01
Project End
2001-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Virginia
Department
Neurology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Kindler, Dean D; Thiffault, Christine; Solenski, Nina J et al. (2003) Neurotoxic nitric oxide rapidly depolarizes and permeabilizes mitochondria by dynamically opening the mitochondrial transition pore. Mol Cell Neurosci 23:559-73
Solenski, Nina J; Kostecki, Vannessa K; Dovey, Serena et al. (2003) Nitric-oxide-induced depolarization of neuronal mitochondria: implications for neuronal cell death. Mol Cell Neurosci 24:1151-69
Solenski, Nina J; diPierro, Charles G; Trimmer, Patricia A et al. (2002) Ultrastructural changes of neuronal mitochondria after transient and permanent cerebral ischemia. Stroke 33:816-24
Solenski, N J; Kwan, A (2000) Attenuation of free radical generation during reversible focal cerebral ischemia with the nitric oxide inhibitor, L-NAME (L-N(G)-nitro-L-arginine methyl ester). Brain Res 862:262-5
Solenski, N J; diPierro, C G; Kassell, N F et al. (2000) Cerebral ischemia-reperfusion injury: a novel therapeutic approach with TAK-218. Clin Neuropharmacol 23:69-74
Solenski, N J; Kwan, A L; Yanamoto, H et al. (1997) Differential hydroxylation of salicylate in core and penumbra regions during focal reversible cerebral ischemia. Stroke 28:2545-51; discussion 2551-2