Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Physician Scientist Award (K11)
Project #
5K11AR001927-03
Application #
2077493
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Project Start
1994-05-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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Routes, J M; Ryan, J C; Ryan, S et al. (2001) MHC class I molecules on adenovirus E1A-expressing tumor cells inhibit NK cell killing but not NK cell-mediated tumor rejection. Int Immunol 13:1301-7
Nakamura, M C; Hayashi, S; Niemi, E C et al. (2000) Activating Ly-49D and inhibitory Ly-49A natural killer cell receptors demonstrate distinct requirements for interaction with H2-D(d). J Exp Med 192:447-54
Nakamura, M C; Linnemeyer, P A; Niemi, E C et al. (1999) Mouse Ly-49D recognizes H-2Dd and activates natural killer cell cytotoxicity. J Exp Med 189:493-500
Nakamura, M C; Naper, C; Niemi, E C et al. (1999) Natural killing of xenogeneic cells mediated by the mouse Ly-49D receptor. J Immunol 163:4694-700
Sundback, J; Nakamura, M C; Waldenstrom, M et al. (1998) The alpha2 domain of H-2Dd restricts the allelic specificity of the murine NK cell inhibitory receptor Ly-49A. J Immunol 160:5971-8
Johansson, M H; Hoglund, E; Nakamura, M C et al. (1998) Alpha1/alpha2 domains of H-2D(d), but not H-2L(d), induce ""missing self"" reactivity in vivo--no effect of H-2L(d) on protection against NK cells expressing the inhibitory receptor Ly49G2. Eur J Immunol 28:4198-206
Nakamura, M C; Niemi, E C; Fisher, M J et al. (1997) Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J Exp Med 185:673-84