Abstract

The candidate will investigate the hypothesis that estrogen-dependent induction of the chicken vitellogenin II gene involves overriding the effects of a negative control element located within the promoter.
Specific aims are directed at understanding the molecular basis for this negative control, including precise descriptions of the cis-acting control element and the factor(s) that binds to it.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Physician Scientist Award (K11)
Project #
5K11CA001689-02
Application #
3085975
Study Section
Cancer Institutional Fellowship Review Committee (CT)
Project Start
1992-08-11
Project End
1995-07-31
Budget Start
1993-08-01
Budget End
1994-07-31
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
Institute for Cancer Research
Department
Type
DUNS #
872612445
City
Philadelphia
State
PA
Country
United States
Zip Code
19111

  Publications

Laverriere, A C; MacNeill, C; Mueller, C et al. (1994) GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. J Biol Chem 269:23177-84