AIMS and METHODS: Phase I (training): To develop independent research skills in the science of bioengineering as related to strabismus muscle mechanisms. The proposed projects are: (1) an electromechanical device to obtain length-tension data on extraocular muscles without the variability inherent in hand-held instruments, (2) continue development of an """"""""expert system"""""""" for strabismus diagnosis, and (3) continue computer simulation of specific cases of human strabismus. Phase II (research): Proposed projects are: (1) continuation of the """"""""expert system"""""""" development, and (2) creation of muscle and nerve prostheses. The """"""""expert system will be mostly a programming effort to simulate a strabismologist's analysis of patient data leading to a specific diagnosis and treatment. The prostheses will be electronic or electromechanical devices intended to replace permanently damaged muscle on nerve. SIGNIFICANCE: This work should (1) allow better diagnosis and treatment of specific cases of strabismus and lead to a reduction in the number of re-operations, and (2) lead to technological alternatives to muscle transposition techniques currently used to restore function in oculomotor palsies.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Physician Scientist Award (K11)
Project #
7K11EY000279-03
Application #
3086726
Study Section
Vision Research and Training Committee (VSN)
Project Start
1986-04-01
Project End
1989-03-31
Budget Start
1986-04-01
Budget End
1987-03-31
Support Year
3
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Smith-Kettlewell Eye Research Institute
Department
Type
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94115