Insulin, the Sodium Pump, and Diabetic Retinopathy

Gardner, Thomas W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Eye Institute (NEI)
• Type: Physician Scientist Award (K11)
• Project #: 5K11EY000331-04
• Application #: 2157828
• Study Section: Vision Research and Training Committee (VSN)
• Project Start: 1993-01-01
• Project End: 1997-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: Pennsylvania State University
• Department: Ophthalmology
• Type: Schools of Medicine
• DUNS #: 129348186
• City: Hershey
• State: PA
• Country: United States
• Zip Code: 17033

Publications

Barber, A J; Lieth, E; Khin, S A et al. (1998) Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin. J Clin Invest 102:783-91

Antonetti, D A; Barber, A J; Khin, S et al. (1998) Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group. Diabetes 47:1953-9

Yaccino, J A; Chang, Y S; Hollis, T M et al. (1997) Physiological transport properties of cultured retinal microvascular endothelial cell monolayers. Curr Eye Res 16:761-8

Gardner, T W; Klein, R; Moss, S E et al. (1995) Digoxin does not accelerate progression of diabetic retinopathy. Diabetes Care 18:237-40

Gardner, T W; Eller, A W; Friberg, T R et al. (1995) Antihistamines reduce blood-retinal barrier permeability in type I (insulin-dependent) diabetic patients with nonproliferative retinopathy. A pilot study. Retina 15:134-40