Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Physician Scientist Award (K11)
Project #
3K11MH000631-03S1
Application #
3087934
Study Section
Research Scientist Development Review Committee (MHK)
Project Start
1986-07-01
Project End
1991-06-30
Budget Start
1989-06-15
Budget End
1989-06-30
Support Year
3
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Zylberman, I; Javitt, D C; Zukin, S R (1995) Pharmacological augmentation of NMDA receptor function for treatment of schizophrenia. Ann N Y Acad Sci 757:487-91
Javitt, D C; Frusciante, M J; Zukin, S R (1994) Activation-related and activation-independent effects of polyamines on phencyclidine receptor binding within the N-methyl-D-aspartate receptor complex. J Pharmacol Exp Ther 270:604-13
Javitt, D C; Zylberman, I; Zukin, S R et al. (1994) Amelioration of negative symptoms in schizophrenia by glycine. Am J Psychiatry 151:1234-6
Javitt, D C; Schroeder, C E; Steinschneider, M et al. (1992) Demonstration of mismatch negativity in the monkey. Electroencephalogr Clin Neurophysiol 83:87-90
Nussenzveig, I Z; Sircar, R; Wong, M L et al. (1991) Polyamine effects upon N-methyl-D-aspartate receptor functioning: differential alteration by glutamate and glycine site antagonists. Brain Res 561:285-91
Javitt, D C; Zukin, S R (1991) Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 148:1301-8
Javitt, D C; Zukin, S R (1990) The role of excitatory amino acids in neuropsychiatric illness. J Neuropsychiatry Clin Neurosci 2:44-52
Javitt, D C; Frusciante, M J; Zukin, S R (1990) Rat brain N-methyl-D-aspartate receptors require multiple molecules of agonist for activation. Mol Pharmacol 37:603-7
Javitt, D C; Zukin, S R (1989) Interaction of [3H]MK-801 with multiple states of the N-methyl-D-aspartate receptor complex of rat brain. Proc Natl Acad Sci U S A 86:740-4
Javitt, D C; Zukin, S R (1989) Biexponential kinetics of [3H]MK-801 binding: evidence for access to closed and open N-methyl-D-aspartate receptor channels. Mol Pharmacol 35:387-93

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