Training in Urology

Wein, Alan J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Physician Scientist Award (Program) (PSA) (K12)
• Project #: 5K12DK002196-03
• Application #: 2133995
• Study Section: Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
• Project Start: 1994-07-01
• Project End: 1999-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Pennsylvania
• Department: Surgery
• Type: Schools of Medicine
• DUNS #: 042250712
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Clement, Michele R; Delaney, Daniel P; Austin, J Christopher et al. (2006) Activation of the calcineurin pathway is associated with detrusor decompensation: a potential therapeutic target. J Urol 176:1225-9

Shukla, Aseem R; Nguyen, Trang; Zheng, Yongmu et al. (2004) Over expression of smooth muscle specific caldesmon by transfection and intermittent agonist induced contraction alters cellular morphology and restores differentiated smooth muscle phenotype. J Urol 171:1949-54

Wu, Hsi-Yang; Zderic, Stephen A; Wein, Alan J et al. (2004) Decrease in maximal force generation in the neonatal mouse bladder corresponds to shift in myosin heavy chain isoform composition. J Urol 171:841-4

Hutcheson, Joel C; Stein, Raimund; Chacko, Samuel et al. (2004) Murine in vitro whole bladder model: a method for assessing phenotypic responses to pharmacologic stimuli and hypoxia. Neurourol Urodyn 23:349-54

Stein, Raimund; Gong, ChaoLiang; Hutcheson, Joel et al. (2003) The fate of urinary bladder smooth muscle after outlet obstruction--a role for the sarcoplasmic reticulum. Adv Exp Med Biol 539:773-90

Stein, R; Hutcheson, J C; Gong, C et al. (2001) The decompensated detrusor IV: experimental bladder outlet obstruction and its functional correlation to the expression of the ryanodine and voltage operated calcium channels. J Urol 165:2284-8

Stein, R; Gong, C; Hutcheson, J C et al. (2000) The decompensated detrusor III: impact of bladder outlet obstruction on sarcoplasmic endoplasmic reticulum protein and gene expression. J Urol 164:1026-30

Nigro, D A; Haugaard, N; Wein, A J et al. (1999) Metabolic basis for contractile dysfunction following chronic partial bladder outlet obstruction in rabbits. Mol Cell Biochem 200:1-6

Zderic, S A; Gong, C; Desanto, M et al. (1999) Calcium ion homeostasis in urinary bladder smooth muscle. Adv Exp Med Biol 462:155-69;discussion 225-33

DiSanto, M E; Wang, Z; Menon, C et al. (1998) Expression of myosin isoforms in smooth muscle cells in the corpus cavernosum penis. Am J Physiol 275:C976-87