The Weill Cornell Medical College (WCMC) Division of Child eurology proposal for a Neurological Sciences Academic Development Award (NSADA) is designed to facilitate and nurture career development for junior faculty Child Neurologists committed to independent research careers and to enable scientific training ofthe next generation of clinical neuroscientists. The Tri-lnstitutional Research Program comprising Weill Cornell Medical College, The Rockefeller University, and the Sloan-Kettering Institute ofthe Memorial Sloan-Kettering Cancer Center provides a unique environment for an NSADA Program. These three institutions recognize the national need for training biomedical investigators who: (A) have advanced understanding of biomedical neuroscience and a mastery of contemporary research skills, which will allow them to undertake fundamental studies to elucidate basic neurobiological processes pertaining to human developmental neurologic disease;and (B) are well grounded in human neurobiology, pathophysiology and clinical neurology, including child neurology. Our program will guide NSADA Scholars through a rigorous course of postgraduate study that offers flexibility regarding the individual focus of research, and unfettered access to experienced mentors in leading developmental neuroscience laboratories within the Tri-lnstitutional campus. The multi-Institutional makeup of the faculty ensures that there is broad expertise in all ofthe major research disciplines comprising developmental neuroscience in its broadest sense: neurochemistry and neurobiology;neuroanatomy and MR- based brain imaging, cell and developmental neurobiology;neuropharmacology;computational neurobiology and bioinformatics;neurogenetics and genomics;neuro-immunology;molecular neuroscience;pathology and mechanisms of disease;and neurophysiology and biophysics. While the framework of developmental neurology and medicine and the sciences ofthe infant's and child's brain in health and disease is vast, our program will emphasize the theme of having each trainee master skills in developmental neurobiology, which enable them to acquire and apply current methods in basic and clinical neurosciences to improve thir ability to diagnose and treat developmental brain disorders.

Public Health Relevance

Our training program will allow the development of clinician researchers with the skills necessary to transfer advances in basic research to the understanding, prevention, and treatment of pediatric neurologic disorders and improve the public health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12NS066274-03
Application #
8299559
Study Section
Special Emphasis Panel (ZNS1-SRB-M (74))
Program Officer
Korn, Stephen J
Project Start
2010-09-01
Project End
2015-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
3
Fiscal Year
2012
Total Cost
$449,712
Indirect Cost
$33,312
Name
Weill Medical College of Cornell University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Patel, Anup D; Berg, Anne T; Billinghurst, Lori et al. (2018) Quality improvement in neurology: Child neurology quality measure set: Executive summary. Neurology 90:67-73
Berg, Anne T; Chakravorty, Samya; Koh, Sookyong et al. (2018) Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One 13:e0193599
Glass, Hannah C; Grinspan, Zachary M; Shellhaas, Renée A (2018) Outcomes after acute symptomatic seizures in neonates. Semin Fetal Neonatal Med :
Grinspan, Zachary M; Shellhaas, Renée A; Coryell, Jason et al. (2018) Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr 172:352-360
Grinspan, Zachary M; Patel, Anup D; Hafeez, Baria et al. (2018) Predicting frequent emergency department use among children with epilepsy: A retrospective cohort study using electronic health data from 2 centers. Epilepsia 59:155-169
Grinspan, Zachary M; Tian, Niu; Yozawitz, Elissa G et al. (2018) Common terms for rare epilepsies: Synonyms, associated terms, and links to structured vocabularies. Epilepsia Open 3:91-97
Shellhaas, Renée A; Berg, Anne T; Grinspan, Zachary M et al. (2017) Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol 75:73-79
Hafeez, Baria; Miller, Sophia; Patel, Anup D et al. (2017) Care coordination at a pediatric accountable care organization (ACO): A qualitative analysis. Epilepsy Behav 73:148-155
Keros, Sotirios; Buraniqi, Ersida; Alex, Byron et al. (2017) Increasing Ketamine Use for Refractory Status Epilepticus in US Pediatric Hospitals. J Child Neurol 32:638-646
Kutscher, Eric J; Joshi, Sucheta M; Patel, Anup D et al. (2017) Barriers to Genetic Testing for Pediatric Medicaid Beneficiaries With Epilepsy. Pediatr Neurol 73:28-35

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