Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Career Transition Award (K22)
Project #
1K22CA084563-01
Application #
6051594
Study Section
Special Emphasis Panel (ZCA1-GRB-J (O1))
Program Officer
Gorelic, Lester S
Project Start
2006-06-20
Project End
2008-05-31
Budget Start
2006-06-20
Budget End
2007-05-31
Support Year
1
Fiscal Year
2006
Total Cost
$164,160
Indirect Cost

  Institution

Name
University of Utah
Department
Neurosurgery
Type
Schools of Medicine
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112

  Publications

Choi, Hyunsung; Gillespie, David L; Berg, Shauna et al. (2015) Intermittent induction of HIF-1? produces lasting effects on malignant progression independent of its continued expression. PLoS One 10:e0125125
Tiburcio, Patricia Denise; Choi, Hyunsung; Huang, L Eric (2014) Complex role of HIF in cancer: the known, the unknown, and the unexpected. Hypoxia (Auckl) 2:59-70
Yoo, Young-Gun; Christensen, Jared; Huang, L Eric (2011) HIF-1? confers aggressive malignant traits on human tumor cells independent of its canonical transcriptional function. Cancer Res 71:1244-52
Hayashi, Masami; Yoo, Yoo Young-Gun; Christensen, Jared et al. (2011) Requirement of evading apoptosis for HIF-1?-induced malignant progression in mouse cells. Cell Cycle 10:2364-72
Yoo, Young-Gun; Christensen, Jared; Gu, Jie et al. (2011) HIF-1? mediates tumor hypoxia to confer a perpetual mesenchymal phenotype for malignant progression. Sci Signal 4:pt4
Yoo, Young-Gun; Hayashi, Masami; Christensen, Jared et al. (2009) An essential role of the HIF-1alpha-c-Myc axis in malignant progression. Ann N Y Acad Sci 1177:198-204
Huang, L E (2008) Carrot and stick: HIF-alpha engages c-Myc in hypoxic adaptation. Cell Death Differ 15:672-7
Hammer, Stefanie; To, Kenneth K-W; Yoo, Young-Gun et al. (2007) Hypoxic suppression of the cell cycle gene CDC25A in tumor cells. Cell Cycle 6:1919-26