Last year, approximately 1,400,000 Americans were diagnosed with cancer, and approximately 560,000 died from it. When one considers the adverse events associated with cancer treatment, the wide constellation and severity of end-of-life symptoms, and the aftermath of bereavement, there is no question that cancer-induced suffering is great and that there is a major need for research in cancer palliative care to relieve this suffering. Dr. Jatoi is a mid-career investigator who is re-submitting a K24 application entitled, """"""""Mentoring and Research in Cancer Palliative Care."""""""" Her career goals are as follows: 1) To conduct rigorous, clinical and translational research in cancer palliative care with the short-term goal of relieving suffering among cancer patients;2) To provide opportunities for career growth in cancer palliative care for a diverse group of young investigators with the long-term goal of, again, relieving suffering among cancer patients. Dr. Jatoi is well suited to meet these career goals. She has conducted multiple clinical and translational studies on cancer palliative care, thus generating over 120 published manuscripts. These studies have focused largely on palliating cancer-associated anorexia and weight loss, but they have also, at times, focused on the management of other cancer-related symptoms. As a mentor and senior author, Dr. Jatoi has published 28 manuscripts with 16 young investigators from highly diverse backgrounds. Finally, the Mayo Clinic Comprehensive Cancer Center holds an unwavering commitment to patient care, a vast clinical trial infrastructure, comprehensive laboratory resources, and a dynamic, highly collaborative environment- thus, further ensuring the success of this application.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24CA131099-05
Application #
8312330
Study Section
Subcommittee G - Education (NCI)
Program Officer
Lim, Susan E
Project Start
2008-09-02
Project End
2014-08-31
Budget Start
2012-09-01
Budget End
2014-08-31
Support Year
5
Fiscal Year
2012
Total Cost
$194,903
Indirect Cost
$14,437
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Tran, Elizabeth; Spiceland, Clayton; Sandhu, Nicole P et al. (2016) Malignant Bowel Obstruction in Patients With Recurrent Ovarian Cancer. Am J Hosp Palliat Care 33:272-5
Van Laar, Emily S; Desai, Jayashri Mehta; Jatoi, Aminah (2015) Professional educational needs for chemotherapy-induced nausea and vomiting (CINV): multinational survey results from 2388 health care providers. Support Care Cancer 23:151-7
Patel, Krishna; Foster, Nathan R; Kumar, Amanika et al. (2015) Hydronephrosis in patients with cervical cancer: an assessment of morbidity and survival. Support Care Cancer 23:1303-9
Jatoi, Aminah; Radecki Breitkopf, Carmen; Foster, Nathan R et al. (2015) A mixed-methods feasibility trial of protein kinase C iota inhibition with auranofin in asymptomatic ovarian cancer patients. Oncology 88:208-13
Breitkopf, Carmen Radecki; Stephens, Elisabeth K; Jatoi, Aminah (2014) Hospice in end-of-life patients with cancer: does it lead to changes in nonhospice health care utilization after stopping cancer treatment? Am J Hosp Palliat Care 31:392-5
Egloff, Heidi; Jatoi, Aminah (2014) Pemetrexed for ovarian cancer: a systematic review of the published literature and a consecutive series of patients treated in a nonclinical trial setting. Case Rep Oncol 7:541-9
Jackson, Amie E; Stephens, Elisabeth K; Jatoi, Aminah (2014) Causes and palliation of transfusion-associated vaginal bleeding in patients with metastatic cancer. Int J Gynecol Cancer 24:172-5
Lim, Ming Y; Stephens, Elisabeth K; Novotny, Paul et al. (2013) Self-perceptions of age among 292 chemotherapy-treated cancer patients: Exploring associations with symptoms and survival. J Geriatr Oncol 4:249-54
Jatoi, Aminah (2013) Anti-inflammatory therapy: exploring exercise, serum-derived bovine immunoglobulin/protein isolates, and ruxolitinib for the cancer-associated weight loss syndrome. Curr Opin Support Palliat Care 7:339-41
Griffin, Benjamin R; Stephens, Elisabeth K; Jatoi, Aminah (2013) Are 5-7 Days of Folic Acid Supplementation Necessary prior to Pemetrexed? Observations from a Case Series. Case Rep Oncol 6:339-42

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