Abstract

This application is for a K-24 Mid-Career Award in Patient-Oriented Research. The candidate, Carlos M. Grilo, Ph.D., is Associate Professor of Psychiatry at the Yale School of Medicine, where he serves as Director of the Eating Disorder Program. Dr. Grilo has an established record of patient-oriented research in eating/weight disorders, with specific expertise in binge eating disorder (BED). Dr. Grilo has a track record of mentoring trainees/faculty in patient research and has received three Minority-Training Supplements. Dr. Grilo currently serves as PI on a NIDDK R01 grant examining different treatments for obese BED patients. The study tests cognitive behavioral therapy (CBT), behavioral weight loss (BWL), and sequenced CBT-BWL, is one major project for the K-24 period, and is described in detail. Dr. Grilo currently serves as PI on a Donaghue Foundation grant testing different guided self-help behavioral treatments for obesity/BED and an American Heart Association grant for a randomized placebo-controlled trial of an obesity medication given concurrently with CBT for obesity/BED. Dr. Grilo previously received, as PI, a NIDDK R29 grant for a randomized placebo-controlled comparative trial testing psychological and pharmacological treatments for BED, and a NIMH R03 for a controlled pharmacologic trial for bulimia nervosa. Dr. Grilo has served as Co-Investigator on several Foundation and NIH grants. Maintaining active support for research in the future is anticipated, particularly if K-24 is awarded to ensure protected time from clinical-administrative duties. The K-24 will allow Dr. Grilo to maintain a research focus on eating/weight disorders. To increase his contributions addressing these major public health problems, the K-24 will allow him to further enhance his effectiveness as an investigator/mentor. Internationally recognized consultants have been secured. Dr. has recruited strong postdoctoral fellows and is well positioned to mentor them and faculty. Funded programs provide unique resources for training the next generation of clinical-researchers of eating/weight disorders

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24DK070052-04
Application #
7431654
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Podskalny, Judith M,
Project Start
2005-07-01
Project End
2010-06-30
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
4
Fiscal Year
2008
Total Cost
$122,805
Indirect Cost

  Institution

Name
Yale University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Rasmusson, Grace; Lydecker, Janet A; Coffino, Jaime A et al. (2018) Household food insecurity is associated with binge-eating disorder and obesity. Int J Eat Disord :
Ivezaj, Valentina; Wiedemann, Ashley A; Lydecker, Janet A et al. (2018) Food addiction among Spanish-speaking Latino/as residing in the United States. Eat Behav 30:61-65
Lydecker, Janet A; O'Brien, Elizabeth; Grilo, Carlos M (2018) Parents have both implicit and explicit biases against children with obesity. J Behav Med 41:784-791
Machado, Paulo P P; Grilo, Carlos M; Crosby, Ross D (2018) Replication of a Modified Factor Structure for the Eating Disorder Examination-Questionnaire: Extension to Clinical Eating Disorder and Non-clinical Samples in Portugal. Eur Eat Disord Rev 26:75-80
Barnes, Rachel D; Ivezaj, Valentina; Martino, Steve et al. (2018) Examining motivational interviewing plus nutrition psychoeducation for weight loss in primary care. J Psychosom Res 104:101-107
Wiedemann, Ashley A; Lawson, Jessica L; Cunningham, Paige M et al. (2018) Food addiction among men and women in India. Eur Eat Disord Rev 26:597-604
Lydecker, Janet A; Shea, Megan; Grilo, Carlos M (2018) Driven exercise in the absence of binge eating: Implications for purging disorder. Int J Eat Disord 51:139-145
Lydecker, Janet A; Grilo, Carlos M (2018) Comparing men and women with binge-eating disorder and co-morbid obesity. Int J Eat Disord 51:411-417
Udo, Tomoko; Grilo, Carlos M (2018) Prevalence and Correlates of DSM-5-Defined Eating Disorders in a Nationally Representative Sample of U.S. Adults. Biol Psychiatry 84:345-354
Barnes, Rachel D; Ivezaj, Valentina; Pittman, Brian P et al. (2018) Early weight loss predicts weight loss treatment response regardless of binge-eating disorder status and pretreatment weight change. Int J Eat Disord 51:558-564

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