Throughout my research career I have I cultivated a passion for mentoring clinical researchers in Nephrology, Epidemiology, and Biostatistics. I have translated this passion into action, as the director of an established and successful clinical research group that integrates physicians, Epidemiologists, and Biostatisticians toward the study of chronic kidney disease, and as chair of the University of Washington Medical School Epidemiology course. My previous research trainees have published extensively during their training period, obtained career development awards, and secured faculty positions in academic medicine. I am applying for this K24 grant to secure the protected time necessary to implement a comprehensive clinical research training program designed to equip the next generation of researchers with vital methodological skills and hands-on research experiences necessary for them to obtain independent funding and achieve long-term success. I will mentor physician-scientists and graduate students in Epidemiology and Biostatistics, who will work together to solve clinical research problems in chronic kidney disease. Trainees will work within the dedicated environment of the Kidney Research Institute (KRI), a kidney-specialized, clinical and translational research unit that provides key infrastructure and support for patient-oriented research.

Public Health Relevance

The purpose of this grant application is to provide Dr. Bryan Kestenbaum, MD MS, with the protected time needed to rigorously train and mentor future clinical researchers in Nephrology. Clinical research trainees who complete this mentorship program will possess the skills, knowledge and preliminary data needed to evolve into successful independent researchers who will advance their scientific field and continue the teaching cycle.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24DK103986-05
Application #
9901518
Study Section
Kidney, Urologic and Hematologic Diseases D Subcommittee (DDK)
Program Officer
Abbott, Kevin C
Project Start
2016-07-01
Project End
2021-03-31
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
5
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Sharma, Arjun; Govindan, Priyanka; Toukatly, Mirna et al. (2018) Heroin Use Is Associated with AA-Type Kidney Amyloidosis in the Pacific Northwest. Clin J Am Soc Nephrol 13:1030-1036
Robinson-Cohen, Cassianne; Lutsey, Pamela L; Kleber, Marcus E et al. (2017) Genetic Variants Associated with Circulating Parathyroid Hormone. J Am Soc Nephrol 28:1553-1565
Roshanravan, Baback; Patel, Kushang V; Fried, Linda F et al. (2017) Association of Muscle Endurance, Fatigability, and Strength With Functional Limitation and Mortality in the Health Aging and Body Composition Study. J Gerontol A Biol Sci Med Sci 72:284-291
Roshanravan, Baback; Kestenbaum, Bryan; Gamboa, Jorge et al. (2016) CKD and Muscle Mitochondrial Energetics. Am J Kidney Dis 68:658-659
van Ballegooijen, Adriana J; Rhee, Eugene P; Elmariah, Sammy et al. (2016) Renal Clearance of Mineral Metabolism Biomarkers. J Am Soc Nephrol 27:392-7