The University of Miami School of Medicine is proposing to develop a school-wide Clinical Research Curriculum (CRC), to attain the following goals: (1) Selecting trainees from a highly-qualified, discipline-diverse, applicant pool; (2) Developing a two-year curriculum that will enrich and strengthen the skills necessary to pursue a career in clinical research; (3) Fostering of the development of mentoring relationships between trainees and faculty; and (4) Evaluating both the trainees and the curriculum as to assure an intensive and highly-rigorous training experience in research methodology. The University of Miami is well positioned to develop a clinical research curriculum with research funding ranking in the top 25% of the existing medical schools, and highly qualified well-funded basic research and clinical investigators. The CRC will be located in the office of the Vice Provost for Research and will consist of the Director, an Advisory Committee, a Curriculum Committee, and a Selection/Evaluation Committee. Through a formal application procedure, ten to fifteen candidates will be selected to participate in the two-year curriculum. Preference will be given to highly- motivated individuals who are supported by NIH-funded F (Fellowship), K (institutional), or T (training) awards. Both the course content and the trainees will be evaluated on a regular schedule. Course contents will include both beginning and advanced courses in cellular biology and transplant immunology. Specialized courses on the use of computers in research and in research in multicultural populations will be offered. Over the five-year period, courses will be adapted to web-based learning in order to make the courses available to a larger number of fellows/postdoctoral trainees, both locally and nationally. This infrastructure will initiate an organized, targeted, school-wide curriculum for the training of individuals interested in careers in clinical research at the University of Miami School of medicine. It will set the benchmark for clinical research standards and will produce well-trained and highly-qualified, clinical investigators who will make significant contributions to the future of medicine.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Research Curriculum Award (CRCA) (K30)
Project #
5K30HL004537-04
Application #
6642084
Study Section
Special Emphasis Panel (ZHL1-CSR-F (S3))
Program Officer
Friedman, Lawerence
Project Start
2000-09-30
Project End
2005-08-31
Budget Start
2003-09-01
Budget End
2004-08-31
Support Year
4
Fiscal Year
2003
Total Cost
$200,000
Indirect Cost
Name
University of Miami School of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
052780918
City
Miami
State
FL
Country
United States
Zip Code
33146
Bansal, Neha; Barach, Paul; Amdani, Shahnawaz M et al. (2018) When is early septal myectomy in children with hypertrophic cardiomyopathy justified? Transl Pediatr 7:362-366
Lipshultz, Steven E (2018) Letter by Lipshultz Regarding Article, ""Anthracycline Cardiotoxicity: Worrisome Enough to Have You Quaking?"" Circ Res 122:e62-e63
Hutchins, Kelley K; Siddeek, Hani; Franco, Vivian I et al. (2017) Prevention of cardiotoxicity among survivors of childhood cancer. Br J Clin Pharmacol 83:455-465
Lipshultz, Steven E; Anderson, Lynn M; Miller, Tracie L et al. (2016) Impaired mitochondrial function is abrogated by dexrazoxane in doxorubicin-treated childhood acute lymphoblastic leukemia survivors. Cancer 122:946-53
Franco, Vivian I; Lipshultz, Steven E (2015) Cardiac complications in childhood cancer survivors treated with anthracyclines. Cardiol Young 25 Suppl 2:107-16
Lipshultz, Steven E; Franco, Vivian I; Miller, Tracie L et al. (2015) Cardiovascular disease in adult survivors of childhood cancer. Annu Rev Med 66:161-76
Lipshultz, Steven E; Chandar, Jayanthi J; Rusconi, Paolo G et al. (2014) Issues in solid-organ transplantation in children: translational research from bench to bedside. Clinics (Sao Paulo) 69 Suppl 1:55-72
Lipshultz, Steven E; Lipsitz, Stuart R; Kutok, Jeffery L et al. (2013) Impact of hemochromatosis gene mutations on cardiac status in doxorubicin-treated survivors of childhood high-risk leukemia. Cancer 119:3555-62
Landy, David C; Lipsitz, Stuart R; Kurtz, Joy M et al. (2013) Dietary quality, caloric intake, and adiposity of childhood cancer survivors and their siblings: an analysis from the cardiac risk factors in childhood cancer survivors study. Nutr Cancer 65:547-55
Landy, David C; Miller, Tracie L; Lipsitz, Stuart R et al. (2013) Cranial irradiation as an additional risk factor for anthracycline cardiotoxicity in childhood cancer survivors: an analysis from the cardiac risk factors in childhood cancer survivors study. Pediatr Cardiol 34:826-34

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