Program Director/Principal Investigator (Last, First, Middle): G r e e n b e r g , H a r r y B. PROJECT SUMIVIARY (See instructions): The mission of Spectrum, the CTSA-supported independent research center at Stanford, is to transform the academic enterprise to optimally support clinical and translational research and education (CTRE). Spectrum's programs are designed to extend from the earliest phase of basic discovery to final implementation of these discoveries in the population. The ultimate goals of our efforts are to streamline the translation of basic innovations into practical solutions that maintain and improve human health, and to educate the next generation of CTR leaders. In the next five years. Spectrum will leverage institutional strengths to nurture our entrepreneurial researchers to efficiently transfer discoveries from the laboratory to the bedside and into the community. The CTSA will provide critical resources, services and educational opportunities to ensure progress toward this mission.
The specific aims of Spectrum are: 1) Educate the next generation of investigators with the multidisciplinary skills required to conduct cutting- edge clinical and translational research to meet the opportunities and challenges of medicine in the 21st century. Spectrum will facilitate the transformation of medical research training from a narrow focus on discipline-restricted expertise to a more interdisciplinary team approach where trainees become conversant in the language, processes and tools used across the full extent of the translational pipeline (T1-T4). 2) Create an institutional home conducive to efficiently translating the most innovative discoveries made by our basic, translational and clinical scientists into products and processes that directly improve human health and well-being. Spectrum will provide the institutional environment to identify and then support those discoveries that are most ready for translation. 3) Develop and implement CTRE resources and services to accelerate the translation of discoveries into better human health, while simultaneously reducing operating costs. Spectrum will ensure that investigators receive the necessary clinical trial, informatics, statistics, regulatory, ethics and administrative support to maximize their research productivity, and optimize the participation of diverse populations.

Public Health Relevance

The mission of Spectrum, Stanford's CTSA-supported center, is to transform the enterprise to best support discovery, innovation and education in clinical and translational research across the university. Spectrum's programs extend from the earliest phase of basic discovery to final implementation in the population, with an ultimate goal of strengthening healthcare and improving cost efficiencies.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Mentored Career Development Award (KL2)
Project #
1KL2TR001083-01
Application #
8720987
Study Section
Special Emphasis Panel (ZAI1-PTM-C (S2))
Program Officer
Wilson, Todd
Project Start
2013-09-26
Project End
2018-04-30
Budget Start
2013-09-26
Budget End
2014-04-30
Support Year
1
Fiscal Year
2013
Total Cost
$306,646
Indirect Cost
$15,761
Name
Stanford University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Kwong, Allison J; Kim, W Ray; Flemming, Jennifer A (2018) De Novo Hepatocellular Carcinoma Among Liver Transplant Registrants in the Direct Acting Antiviral Era. Hepatology 68:1288-1297
Wei, Mike; Ford, Jason; Li, Qihan et al. (2018) Hospital Cirrhosis Volume and Readmission in Patients with Cirrhosis in California. Dig Dis Sci 63:2267-2274
Ananieva, Elitsa A; Wilkinson, Adam C (2018) Branched-chain amino acid metabolism in cancer. Curr Opin Clin Nutr Metab Care 21:64-70
Ho, Annabell; Hancock, Jeff; Miner, Adam S (2018) Psychological, Relational, and Emotional Effects of Self-Disclosure After Conversations With a Chatbot. J Commun 68:712-733
Mooney, Joshua J; Hedlin, Haley; Mohabir, Paul et al. (2018) Racial and ethnic disparities in lung transplant listing and waitlist outcomes. J Heart Lung Transplant 37:394-400
Horton, Timothy M; Allegretti, Paul A; Lee, Sooyeon et al. (2018) Zinc-Chelating Small Molecules Preferentially Accumulate and Function within Pancreatic ? Cells. Cell Chem Biol :
Yu, Jessica X; Oliver, Melissa; Lin, Jody et al. (2018) Patients Prescribed Direct-acting Oral Anticoagulants Have Low Risk of Post-Polypectomy Complications. Clin Gastroenterol Hepatol :
Kwong, Allison J; Wall, Anji; Melcher, Marc et al. (2018) Liver transplantation for hepatitis C virus (HCV) non-viremic recipients with HCV viremic donors. Am J Transplant :
Knowles, Juliet K; Santoro, Jonathan D; Porter, Brenda E et al. (2018) Refractory focal epilepsy in a paediatric patient with primary familial brain calcification. Seizure 56:50-52
Baumer, Fiona M; Cardon, Aaron L; Porter, Brenda E (2018) Language Dysfunction in Pediatric Epilepsy. J Pediatr 194:13-21

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