This is a study to evaluate the tolerability and effectiveness of Rofecoxib 25 mg. q.d. vs. Naproxen 500 mg. B.I.D. after 12 weeks of treatment in patient with osteoarthritis of the knee, hip, hand, or spine. Osteoarthritis will be diagnosed with standardized clinical criteria. Patients who regularly use non steroidal anti-inflammatory or acetaminophen for the treatment of osteoarthritis of the study joint will be studied. The primary aim is to test the gastrointestinal tolerability of the investigational drug.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000080-38
Application #
6420890
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1978-12-01
Project End
2003-11-30
Budget Start
Budget End
Support Year
38
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
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