Abstract

To understand the potential influences of endogenous and exogenous hormones and other agents on the immune function of the female reproductive tract. This will provide a foundation for future studies including various immunization protocols to induce immune responses in human gential tract. We will compare the immunologic effect of a number oa agents on samples of blood, saliva cervico-vaginal fluids and some tissue samples (servical Biopsy) that we obtain at different times of the menstrual cycle and/or reporductive life.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000211-34A2
Application #
6219758
Study Section
Project Start
1999-08-16
Project End
1999-11-30
Budget Start
Budget End
Support Year
34
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Tennessee Health Science Center
Department
Type
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163

  Publications

Nyenwe, Ebenezer; Owei, Ibiye; Wan, Jim et al. (2018) Parental History of Type 2 Diabetes Abrogates Ethnic Disparities in Key Glucoregulatory Indices. J Clin Endocrinol Metab 103:514-522
Messier, Stephen P; Resnik, Allison E; Beavers, Daniel P et al. (2018) Intentional Weight Loss in Overweight and Obese Patients With Knee Osteoarthritis: Is More Better? Arthritis Care Res (Hoboken) 70:1569-1575
Sanders, John T; Hastings, M Colleen; Moldoveanu, Zina et al. (2017) Serial Galactose-Deficient IgA1 Levels in Children with IgA Nephropathy and Healthy Controls. Int J Nephrol 2017:8210641
Pogacnik Murillo, Aarón Leonardo; Eckstein, Felix; Wirth, Wolfgang et al. (2017) Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial. Cells Tissues Organs 203:258-266
Messier, S P; Beavers, D P; Herman, C et al. (2016) Are unilateral and bilateral knee osteoarthritis patients unique subsets of knee osteoarthritis? A biomechanical perspective. Osteoarthritis Cartilage 24:807-13
Boucher, Andrew B; Adesanya, E A Omoluyi; Owei, Ibiye et al. (2015) Dietary habits and leisure-time physical activity in relation to adiposity, dyslipidemia, and incident dysglycemia in the pathobiology of prediabetes in a biracial cohort study. Metabolism 64:1060-7
Hunter, D J; Beavers, D P; Eckstein, F et al. (2015) The Intensive Diet and Exercise for Arthritis (IDEA) trial: 18-month radiographic and MRI outcomes. Osteoarthritis Cartilage 23:1090-8
Ebenibo, Sotonte; Edeoga, Chimaroke; Wan, Jim et al. (2014) Glucoregulatory function among African Americans and European Americans with normal or pre-diabetic hemoglobin A1c levels. Metabolism 63:767-72
Dagogo-Jack, Samuel; Edeoga, Chimaroke; Ebenibo, Sotonte et al. (2014) Lack of racial disparity in incident prediabetes and glycemic progression among black and white offspring of parents with type 2 diabetes: the pathobiology of prediabetes in a biracial cohort (POP-ABC) study. J Clin Endocrinol Metab 99:E1078-87
Messier, S P; Pater, M; Beavers, D P et al. (2014) Influences of alignment and obesity on knee joint loading in osteoarthritic gait. Osteoarthritis Cartilage 22:912-7

Showing the most recent 10 out of 185 publications