Two Doses of 2,3'-Ddi in Children with HIV Either Responsive or Intolerant to Zdv

Bryson, Yvonne J.

Abstract

Study objectives are to evaluate the long term (48 weeks) safety, tolerance and efficacy of DDI at 50 mg/m2 taken orally every 12 hours in children w/symptomatic HIV infection who have developed toxicity during prolonged zidovudine therapy or who have demonstrated disease progression after 6 months of ZDV therapy.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Center for Research Resources (NCRR)
• Type: General Clinical Research Centers Program (M01)
• Project #: 5M01RR000865-22
• Application #: 3743616
• Support Year: 22
• Fiscal Year: 1995

Institution

• Name: University of California Los Angeles
• DUNS #: 119132785
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90095

Publications

Nersesian, Paula V; Han, Hae-Ra; Yenokyan, Gayane et al. (2018) Loneliness in middle age and biomarkers of systemic inflammation: Findings from Midlife in the United States. Soc Sci Med 209:174-181

Glei, Dana A; Goldman, Noreen; Ryff, Carol D et al. (2018) Physical Function in U.S. Older Adults Compared With Other Populations: A Multinational Study. J Aging Health :898264318759378

Stephan, Yannick; Sutin, Angelina R; Bayard, Sophie et al. (2018) Personality and sleep quality: Evidence from four prospective studies. Health Psychol 37:271-281

Green, Shulamite A; Hernandez, Leanna M; Bowman, Hilary C et al. (2018) Sensory over-responsivity and social cognition in ASD: Effects of aversive sensory stimuli and attentional modulation on neural responses to social cues. Dev Cogn Neurosci 29:127-139

Ellsworth, G B; Lensing, S Y; Ogilvie, C B et al. (2018) A delayed dose of quadrivalent human papillomavirus vaccine demonstrates immune memory in HIV-1-infected men. Papillomavirus Res 6:11-14

Goldman, Noreen; Glei, Dana A; Weinstein, Maxine (2018) Declining mental health among disadvantaged Americans. Proc Natl Acad Sci U S A 115:7290-7295

Dean, Andy C; Morales, Angelica M; Hellemann, Gerhard et al. (2018) Cognitive deficit in methamphetamine users relative to childhood academic performance: link to cortical thickness. Neuropsychopharmacology 43:1745-1752

Ringman, John M; Casado, Maria; Van Berlo, Victoria et al. (2017) A novel PSEN1 (S230N) mutation causing early-onset Alzheimer's Disease associated with prosopagnosia, hoarding, and Parkinsonism. Neurosci Lett 657:11-15

Schwartz, Joseph A (2017) Long-term physical health consequences of perceived inequality: Results from a twin comparison design. Soc Sci Med 187:184-192

Bei, Bei; Seeman, Teresa E; Carroll, Judith E et al. (2017) Sleep and Physiological Dysregulation: A Closer Look at Sleep Intraindividual Variability. Sleep 40: