Diastolic dysfunction is a common cause of congestive heart failure (CHF), particularly among the elderly. Exercise intolerance is a prominent symptom of CHF and an important cause of disability.
The aim of this study is to test the hypotheses that exercise intolerance is associated with diminished ability to increase end-diastolic volume during exercise, and that exercise training will improve exercise tolerance and end-diastolic volume (LV distensibility).

Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
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