This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The main objective of this study is to evaluate the role of sympathetic nervous system in neurovascular control in patients with diastolic heart failure. In this protocol, the investigators plan to study muscle sympathetic nerve activity and plasma norepinephrine levels in patients with chronic heart failure due to diastolic heart dysfunction during rest, exercise (handgrip exercise) and orthostatic stress (head up tilt). They also plan to study the effects of exercise on renal blood flow in these patients.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR010732-15
Application #
7951237
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2009-04-01
Project End
2010-03-31
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
15
Fiscal Year
2009
Total Cost
$1,848
Indirect Cost
Name
Pennsylvania State University
Department
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
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