Abstract

This contract provides an Aged Cell Bank to obtain, characterize, store and distribute cell lines of use to investigators in the field of aging research. These include human cell lines from youth to extreme old age and animal cell lines including primates, rodents and large animals. Cell lines from patients with disease states specific to old age such as osteoporosis and Alzheimer's Disease are targeted for inclusion, as are large families for genetic analysis. Fibroblast, lymphoblastoid, and some differentiated cell lines are included. DNA panels from some of the cell lines are also provided by the Aged Cell Bank.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research and Development Contracts (N01)
Project #
N01AG002101-000
Application #
6316384
Study Section
Project Start
2000-05-01
Project End
2009-01-31
Budget Start
2000-05-01
Budget End
2001-01-31
Support Year
Fiscal Year
2000
Total Cost
$782,824
Indirect Cost

  Institution

Name
Coriell Institute for Medical Research
Department
Type
DUNS #
069894707
City
Camden
State
NJ
Country
United States
Zip Code
08103

  Publications

Gencer, Baris; Butler, Javed; Bauer, Douglas C et al. (2014) Association of electrocardiogram abnormalities and incident heart failure events. Am Heart J 167:869-75.e3
Stawski, Robert S; Almeida, David M; Lachman, Margie E et al. (2010) Fluid cognitive ability is associated with greater exposure and smaller reactions to daily stressors. Psychol Aging 25:330-42
Sliwinski, Martin J; Almeida, David M; Smyth, Joshua et al. (2009) Intraindividual change and variability in daily stress processes: findings from two measurement-burst diary studies. Psychol Aging 24:828-40
Chitko-McKown, C G; Leonard, J C; Moscatello, D et al. (2008) Development of cell lines from the sheep used to construct the CHORI-243 Ovine BAC library. Anim Biotechnol 19:84-8
Jackson, R A; Vittinghoff, E; Kanaya, A M et al. (2004) Urinary incontinence in elderly women: findings from the Health, Aging, and Body Composition Study. Obstet Gynecol 104:301-7
Taylor Jr, Donald H; Fillenbaum, Gerda; Burchett, Bruce et al. (2003) Is the APOE epsilon4 genotype associated with higher hospital costs among elderly patients? Am J Geriatr Psychiatry 11:75-82
Cristofalo, Vincent J; Beck, Jeanne; Allen, R G (2003) Cell senescence: an evaluation of replicative senescence in culture as a model for cell aging in situ. J Gerontol A Biol Sci Med Sci 58:B776-9; discussion 779-81
Blazer, Dan G; Burchett, Bruce B; Fillenbaum, Gerda G (2002) APOE epsilon4 and low cholesterol as risks for depression in a biracial elderly community sample. Am J Geriatr Psychiatry 10:515-20
Blazer, Dan G; Moody-Ayers, Sandra; Craft-Morgan, Jennifer et al. (2002) Depression in diabetes and obesity: racial/ethnic/gender issues in older adults. J Psychosom Res 53:913-6
Blazer, D G; Fillenbaum, G; Burchett, B (2001) The APOE-E4 allele and the risk of functional decline in a community sample of African American and white older adults. J Gerontol A Biol Sci Med Sci 56:M785-9