The purpose of the study is to address the issue of how alterations in arterial stiffness that occur with adult aging affect the myocardium. The interaction of age, arterial pressure, and vascular stiffness on myocardial structure and function shall be addressed by simultaneous measurements of those parameters in a population that is genetically homogeneous but is comprised of individuals in a broad age range who exhibit a spectrum of arterial stiffness. The study population shall consist of a minimum of 800 individuals of each sex evenly distributed across the age range of 20 to 90-100 years who are free of clinical diseases (except hypertension) that can affect arterial or cardiac properties.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research and Development Contracts (N01)
Project #
N01AG012118-001
Application #
2294079
Study Section
Project Start
1991-09-30
Project End
1993-12-31
Budget Start
1992-09-28
Budget End
1993-05-31
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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