Evaluation of AIDS Therapies in Animal Retroviral Models

Tasi, Che-Chung

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research and Development Contracts (N01)
• Project #: N01AI015120-007
• Application #: 2295138
• Project Start: 1991-07-08
• Project End: 1996-07-07
• Budget Start: 1994-02-08
• Budget End: 1995-07-07
• Fiscal Year: 1994

Institution

• Name: University of Washington
• Type: Other Domestic Higher Education
• DUNS #: 135646524
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98195

Publications

Tsai, C C; Emau, P; Sun, J C et al. (2000) Post-exposure chemoprophylaxis (PECP) against SIV infection of macaques as a model for protection from HIV infection. J Med Primatol 29:248-58

Tsai, C C; Emau, P; Follis, K E et al. (1998) Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment. J Virol 72:4265-73

Tsai, C C; Follis, K E; Beck, T W et al. (1997) Effects of (R)-9-(2-phosphonylmethoxypropyl)adenine monotherapy on chronic SIV infection in macaques. AIDS Res Hum Retroviruses 13:707-12

Tsai, C C; Follis, K E; Sabo, A et al. (1995) Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine. Science 270:1197-9

Tsai, C C; Follis, K E; Grant, R F et al. (1993) Infectivity and pathogenesis of titered dosages of simian immunodeficiency virus experimentally inoculated into longtailed macaques (Macaca fascicularis). Lab Anim Sci 43:411-6