Project Start
1987-09-01
Project End
1992-08-31
Budget Start
1989-12-13
Budget End
1990-08-31
Support Year
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Ruprecht, R M; Bronson, R (1994) Chemoprevention of retroviral infection: success is determined by virus inoculum strength and cellular immunity. DNA Cell Biol 13:59-66
Sharpe, A H; Jaenisch, R (1993) Retroviral spongiform degenerative disease produced by the murine neurotropic retrovirus Cas-Br-E. Dev Biol Stand 80:45-52
Ruprecht, R M; Fratazzi, C; Sharma, P L et al. (1993) Animal models for perinatal transmission of pathogenic viruses. Ann N Y Acad Sci 693:213-28
Ruprecht, R M; Koch, J A; Sharma, P L et al. (1992) Development of antiviral treatment strategies in murine models. AIDS Res Hum Retroviruses 8:997-1011
Ruprecht, R M; Chou, T C; Chipty, F et al. (1990) Interferon-alpha and 3'-azido-3'-deoxythymidine are highly synergistic in mice and prevent viremia after acute retrovirus exposure. J Acquir Immune Defic Syndr 3:591-600
Ruprecht, R M; Mullaney, S; Bernard, L D et al. (1990) Vaccination with a live retrovirus: the nature of the protective immune response. Proc Natl Acad Sci U S A 87:5558-62
Ruprecht, R M; Bernard, L D; Gama Sosa, M A et al. (1990) Murine models for evaluating antiretroviral therapy. Cancer Res 50:5618S-5627S
Ruprecht, R M; Mullaney, S; Andersen, J et al. (1989) In vivo analysis of castanospermine, a candidate antiretroviral agent. J Acquir Immune Defic Syndr 2:149-57
Ruprecht, R M (1989) Murine models for antiretroviral therapy. Intervirology 30 Suppl 1:2-11
Sharpe, A H; Hunter, J J; Ruprecht, R M et al. (1989) Maternal transmission of retroviral disease and strategies for preventing infection of the neonate. J Virol 63:1049-53

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