Abstract

The specific objective of this contract is to study the epidemiology and natural history of HIV infection in the heterosexually active population. The information generated by this contract is for the direct benefit and use of the Government in its efforts to describe the natural history of HIV infection among heterosexuals at risk for AIDS. Understanding the epidemiology of AIDS is an essential part of the overall effort to determine how to prevent or treat AIDS in the United States. Another contract shall be awarded for Part I to the Research Foundation of the State University of New York (SUNY) for the period 12/15/88-12/14/93, Contract No. N01-AI-95014. A contract shall be awarded to the University of Michigan, contract no. N01-AI-95015, for the Data Coordinating Center, Part II under this RFP for the same period of performance.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research and Development Contracts (N01)
Project #
N01AI095013-009
Application #
2297453
Study Section
Project Start
1988-12-15
Project End
1993-12-14
Budget Start
1993-01-19
Budget End
1993-12-14
Support Year
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
University of Medicine & Dentistry of NJ
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Newark
State
NJ
Country
United States
Zip Code
07107

  Publications

Shacklett, Barbara L; Means, Robert E; Larsson, Marie et al. (2002) Dendritic cell amplification of HIV type 1-specific CD8+ T cell responses in exposed, seronegative heterosexual women. AIDS Res Hum Retroviruses 18:805-15
Denny, T N; Skurnick, J H; Palumbo, P et al. (1998) CD3+CD8+ cell levels as predictors of transmission in human immunodeficiency virus-infected couples: a report from the heterosexual HIV transmission study. Int J Infect Dis 2:186-92
Rohowsky-Kochan, C; Skurnick, J; Molinaro, D et al. (1998) HLA antigens associated with susceptibility/resistance to HIV-1 infection. Hum Immunol 59:802-15
Skurnick, J H; Kennedy, C A; Perez, G et al. (1998) Behavioral and demographic risk factors for transmission of human immunodeficiency virus type 1 in heterosexual couples: report from the Heterosexual HIV Transmission Study. Clin Infect Dis 26:855-64
Skurnick, J H; Bogden, J D; Baker, H et al. (1996) Micronutrient profiles in HIV-1-infected heterosexual adults. J Acquir Immune Defic Syndr Hum Retrovirol 12:75-83
Denny, T N; Skurnick, J H; Garcia, A et al. (1996) Lymphocyte immunoregulatory cells present in semen from human immunodeficiency virus (HIV)-infected individuals: a report from the HIV Heterosexual Transmission Study. Cytometry 26:47-51
Kennedy, C A; Skurnick, J H; Foley, M et al. (1995) Gender differences in HIV-related psychological distress in heterosexual couples. AIDS Care 7 Suppl 1:S33-8
Denny, T N; Scolpino, A; Garcia, A et al. (1995) Evaluation of T-lymphocyte subsets present in semen and peripheral blood of healthy donors: a report from the heterosexual transmission study. Cytometry 20:349-55
Palumbo, P; Skurnick, J; Lewis, D et al. (1995) PCR analysis of HIV-seronegative, heterosexual partners of HIV-infected individuals. J Acquir Immune Defic Syndr Hum Retrovirol 10:436-40
Foley, M; Skurnick, J H; Kennedy, C A et al. (1994) Family support for heterosexual partners in HIV-serodiscordant couples. AIDS 8:1483-7