The objective of this Master Agreement Order is to conduct an Acute Toxicity Study (rats only), a Pilot Dose Range Finding Study in rats and dogs, and a 13-week Subchronic Toxicity Study in rats and dogs applied to Diallyl Disulfide.
| Crowell, J A; Page, J G; Rodman, L E et al. (1997) Chronic toxicity studies of 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione, a potential chemopreventive agent. Fundam Appl Toxicol 35:9-21 |
