Identify characteristics of Latin American women that are predictive of risk of developing invasive cervical cancer. Identify unusual behavioral characteristics of Latin males that may contribute to the high rates of cervical cancer. Relate certain biochemical indicators (e.g., infectious agents, micronutrients), as measured in both males and females, to risk of cervical cancer. Assessment of the role of infectious agents in males may be particularly informative, sinceresults are not subject to problems encountered in women.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Epidemiology And Genetics (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CP041026-001
Application #
3629613
Study Section
Project Start
1984-09-28
Project End
1987-12-27
Budget Start
1985-12-28
Budget End
1986-12-27
Support Year
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Gorgas Memorial Institute of Trop & Prev Med
Department
Type
DUNS #
City
Bethesda
State
MD
Country
United States
Zip Code
20814
Herrero, R; Brinton, L A; Hartge, P et al. (1993) Determinants of the geographic variation of invasive cervical cancer in Costa Rica. Bull Pan Am Health Organ 27:15-25
Herrero, R; Brinton, L A; Reeves, W C et al. (1992) Screening for cervical cancer in Latin America: a case-control study. Int J Epidemiol 21:1050-6
Brinton, L A; Herrero, R; Brenes, M et al. (1991) Considerations for conducting epidemiologic case-control studies of cancer in developing countries. Bull Pan Am Health Organ 25:1-15
Herrero, R; Potischman, N; Brinton, L A et al. (1991) A case-control study of nutrient status and invasive cervical cancer. I. Dietary indicators. Am J Epidemiol 134:1335-46
Potischman, N; Brinton, L A; Laiming, V A et al. (1991) A case-control study of serum folate levels and invasive cervical cancer. Cancer Res 51:4785-9
Herrero, R; Brinton, L A; Reeves, W C et al. (1990) [The risk factors of invasive carcinoma of the cervix uteri in Latin America] Bol Oficina Sanit Panam 109:6-26
Herrero, R; Brinton, L A; Reeves, W C et al. (1990) Sexual behavior, venereal diseases, hygiene practices, and invasive cervical cancer in a high-risk population. Cancer 65:380-6
Herrero, R; Brinton, L A; Reeves, W C et al. (1990) Risk factors for invasive carcinoma of the uterine cervix in Latin America. Bull Pan Am Health Organ 24:263-83
Mann, V M; de Lao, S L; Brenes, M et al. (1990) Occurrence of IgA and IgG antibodies to select peptides representing human papillomavirus type 16 among cervical cancer cases and controls. Cancer Res 50:7815-9
Brinton, L A; Reeves, W C; Brenes, M M et al. (1989) Parity as a risk factor for cervical cancer. Am J Epidemiol 130:486-96