Abstract

The objective of this contract is to provide cytogenetic support for epidemiologic studies of persons exposed to ionizing radiation. The contractor will provide shipping materials and blood drawing instructions to other NCT contractors; will create and maintain a log of blood specimens received, and perform cytogenetic evaluation including fluorescent in-situ hybridization for translocation analysis. Results of cytogenetic evaluatIons will be reported to NCI.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Epidemiology And Genetics (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CP050520-001
Application #
3701796
Study Section
Project Start
1995-01-23
Project End
1998-01-22
Budget Start
1996-03-07
Budget End
1996-06-30
Support Year
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Moser, M J; Bigbee, W L; Grant, S G et al. (2000) Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes. Cancer Res 60:2492-6
Littlefield, L G; McFee, A F; Salomaa, S I et al. (1998) Do recorded doses overestimate true doses received by Chernobyl cleanup workers? Results of cytogenetic analyses of Estonian workers by fluorescence in situ hybridization. Radiat Res 150:237-49
Jensen, R H; Reynolds, J C; Robbins, J et al. (1997) Glycophorin A as a biological dosimeter for radiation dose to the bone marrow from iodine-131. Radiat Res 147:747-52
Inskip, P D; Hartshorne, M F; Tekkel, M et al. (1997) Thyroid nodularity and cancer among Chernobyl cleanup workers from Estonia. Radiat Res 147:225-35
Bigbee, W L; Jensen, R H; Veidebaum, T et al. (1997) Biodosimetry of Chernobyl cleanup workers from Estonia and Latvia using the glycophorin A in vivo somatic cell mutation assay. Radiat Res 147:215-24
Bigbee, W L; Jensen, R H; Veidebaum, T et al. (1996) Glycophorin A biodosimetry in Chernobyl cleanup workers from the Baltic countries. BMJ 312:1078-9