The specific objectives of this contract are (1) to develop some small fish species as suitable models for carcinogenesis bioassays, and then (2) to test those models with a number of common water contaminants, emphasizing those that are a result of the chlorination of municipal water supplies -- the so-called trihalomethanes.
| Hawkins, W E; Walker, W W; James, M O et al. (1998) Carcinogenic effects of 1,2-dibromoethane (ethylene dibromide;EDB) in Japanese medaka (Oryzias latipes). Mutat Res 399:221-32 |
