The objectives of this study are to provide new knowledge about the risk of second primary lung cancer due to radiation and chemotherapy for breast cancer and Hodgkin's disease, and to quantify risk among longterm survivors. Histopathologic material for molecular analyses and diagnostic confirmation will also be collected. Overall it is envisioned that rosters of patients with breast cancer or Hodgkin's disease will undergo computer linkage with registry reports of second primary lung cancers. Detailed information on initial and subsequent courses of therapy will be abstracted for patients who developed subsequent lung cancer and a matched control group without second primary cancers.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Epidemiology And Genetics (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CP061120-000
Application #
2305382
Study Section
Project Start
1996-03-13
Project End
1998-03-12
Budget Start
1996-03-13
Budget End
1997-03-12
Support Year
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Research Triangle Institute
Department
Type
DUNS #
131606022
City
Research Triangle Park
State
NC
Country
United States
Zip Code
27709
Travis, Lois B; Hill, Deirdre A; Dores, Graca M et al. (2003) Breast cancer following radiotherapy and chemotherapy among young women with Hodgkin disease. JAMA 290:465-75