The purpose of this project is to procure the toxicologic evaluation, in animals, of oral iron chelating compounds, for use in the safe and effective removal of iron deposits in patients with iron overload conditions (e.g., Cooley's anemia, an orphan disease). A clinical evaluation is not desired at this time. The contractor shall conduct toxicologic and related studies of selected iron chelating compounds, in rats, dogs, and other animals as directed by the Project Officer, and shall provide resulting toxicologic information to the NIDDK for use in preparing submissions to the Food and Drug Administration for approval of eventual clinical studies. The drugs under development are considered to be orphan drugs.

Project Start
1993-03-03
Project End
1999-09-30
Budget Start
1998-12-31
Budget End
1999-09-30
Support Year
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Sri International
Department
Type
DUNS #
City
Menlo Park
State
CA
Country
United States
Zip Code
94025