Within the past 25 years the number of chemicals introduced into the environment has increased dramatically. Surprisingly, there is relatively little known about the toxicologic and/or carcinogenic potential of many of them, even though their use may be widespread and the potential for human exposure is relatively high. The National Toxicology Program is attempting to fill this gap in knowledge through the sponsorship of well-defined bioassay evaluations on a number of these materials. As part of this program, the studies conducted under this contract were designed to establish basic toxicity data on specific chemicals, including Disperse Blue 1, H.C.Blue 2, Nitrofurantoin, Rhodamine 6G, H.C.Red 3, Chlorowax 500C, Acid Orange 3, Dichlorvos, Chlorowax 40, Roxarsone, and Pentachloroanisole, using Fischer 344 rats and B6C3F1 mice. Then, based on the data obtained, additional testing in the form of long-term toxicologic/carcinogenic evaluations are pursued in order to provide sufficient data to establish the relative safety or hazard to humans.

Project Start
1982-05-31
Project End
1987-04-30
Budget Start
1989-09-28
Budget End
1988-06-30
Support Year
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Southern Research Institute
Department
Type
DUNS #
006900526
City
Birmingham
State
AL
Country
United States
Zip Code
35205