The proposed research will provide testing of chemical agents for their potential to cause teratogenicity and developmental toxicity. This will be a primary effort for the developmental toxicity testing of chemicals designed for study under the National Toxicology Program.

Project Start
1983-09-29
Project End
1988-09-29
Budget Start
1986-06-03
Budget End
1987-09-28
Support Year
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Research Triangle Institute
Department
Type
DUNS #
131606022
City
Research Triangle Park
State
NC
Country
United States
Zip Code
27709
Field, E A; Price, C J; Sleet, R B et al. (1993) Developmental toxicity evaluation of diethyl and dimethyl phthalate in rats. Teratology 48:33-44
George, J D; Price, C J; Marr, M C et al. (1992) The developmental toxicity of ethylene glycol diethyl ether in mice and rabbits. Fundam Appl Toxicol 19:15-25
Marr, M C; Price, C J; Myers, C B et al. (1992) Developmental stages of the CD (Sprague-Dawley) rat skeleton after maternal exposure to ethylene glycol. Teratology 46:169-81
Williams, J; Price, C J; Sleet, R B et al. (1991) Codeine: developmental toxicity in hamsters and mice. Fundam Appl Toxicol 16:401-13
Lindstrom, P; Morrissey, R E; George, J D et al. (1990) The developmental toxicity of orally administered theophylline in rats and mice. Fundam Appl Toxicol 14:167-78
Field, E A; Price, C J; Sleet, R B et al. (1990) Developmental toxicity evaluation of acrylamide in rats and mice. Fundam Appl Toxicol 14:502-12
George, J D; Price, C J; Marr, M C et al. (1989) Developmental toxicity of 1,1,1-trichloroethane in CD rats. Fundam Appl Toxicol 13:641-51
George, J D; Price, C J; Kimmel, C A et al. (1987) The developmental toxicity of triethylene glycol dimethyl ether in mice. Fundam Appl Toxicol 9:173-81
Price, C J; Kimmel, C A; George, J D et al. (1987) The developmental toxicity of diethylene glycol dimethyl ether in mice. Fundam Appl Toxicol 8:115-26