Georgetown University is conducting a natural history study of chronic non-A, non-B (NANB) hepatitis. The overall objective of the five-year retrospective epidemiologic study is to determine the clinical, biochemical, and histological information on patients who developed posttransfusion hepatitis (PTH) and compare it with transfusion recipients who did not develop PTH. Specifically the contractor must: 1) identify patients who developed NANB PTH in previously completed prospective studies, as well as a group of controls from the same studies; 2) locate the medical records of all individuals identified and invite the survivors to participate. This would include an initial re-evaluation (history, physical examination, and biochemical tests); and 3) follow patients from both groups at six-month intervals for three years. Subjects defined as having had acute NANB PTH in previous studies (specifically, the Transfusion-Trans-mitted Virus Study, and the Veterans Administration Cooperative Study of Posttransfusion Hepatitis) must be identified and the supporting data confirming the diagnosis and form of hepatitis (icteric or anicteric) must be made available.

Agency
National Institute of Health (NIH)
Institute
Division of Blood Diseases And Resources (NHLBI)
Type
Research and Development Contracts (N01)
Project #
N01HB087047-000
Application #
3646270
Study Section
Project Start
1988-03-31
Project End
1993-03-30
Budget Start
1988-03-31
Budget End
1989-03-30
Support Year
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Georgetown University
Department
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057