This project, """"""""Development of a Contraceptive Vaccine"""""""" represents a continuation of research of the development of a promising contraceptive vaccine previously supported by the grant mechanism. The major objective of this contract is to develop a contraceptive vaccine based on the gonadotropin releasing hormone (GnRH).
Vargas, Louis; Sewell, Richard; Marshall, Aileen et al. (2005) Immune complex deposition in adult male Sprague-Dawley rats chronically immunized with GnRH. Am J Reprod Immunol 54:292-310 |
Kumar, N; Savage, T; DeJesus, W et al. (2000) Chronic toxicity and reversibility of antifertility effect of immunization against gonadotropin-releasing hormone in male rats and rabbits. Toxicol Sci 53:92-9 |