Abstract

The objectives of this contract are 1) to purify, isolate and characterize gonadal polypeptides from porcine follicular fluid (particularly FSH-releasing peptides, GnRH-like factor(s), GnRH blocking factor(s), Gn potentiating factor(s), follicular cell regulatory factor(s) and TGF-Beta-like factor(s)), and 2) to prepare partially purified polypeptide factors for distribution by the Government after independent verification of the level of biological activity has been obtained.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research and Development Contracts (N01)
Project #
N01HD062943-001
Application #
3652385
Study Section
Project Start
1986-09-30
Project End
1989-09-29
Budget Start
1987-02-09
Budget End
1988-09-29
Support Year
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
Salk Institute for Biological Studies
Department
Type
DUNS #
005436803
City
La Jolla
State
CA
Country
United States
Zip Code
92037

  Publications

Vale, W; Rivier, C; Hsueh, A et al. (1988) Chemical and biological characterization of the inhibin family of protein hormones. Recent Prog Horm Res 44:1-34