Perform those tasks necessary for the development and continued maintenance and supply of the nonhuman primate as a model for the investigation of arteriosclerosis, hypertension, cerebrovascular disease, or dyslipoproteiemia. Introduce, maintain, and hold animals in the modelling protocol, insure adequate disease screening and control, and breed, model, and raise the offspring, and selectively breed heritable characteristics of interest, specifically atherosclerosis. Monitor metabolic and cardiovascular or cerebrovascular measurements, such as lipids, lipoproteins, ECG, and blood pressure, as well as screening for the dyslipoproteinemic or hypertensive animal.
| Shively, C A; Clarkson, T B; Miller, L C et al. (1987) Body fat distribution as a risk factor for coronary artery atherosclerosis in female cynomolgus monkeys. Arteriosclerosis 7:226-31 |
| Wang, C S; Weingand, K W; Anthony, M S (1987) Effect of atherogenic diet on lipoprotein lipase activity in cynomolgus monkeys. Atherosclerosis 67:173-80 |
| Weingand, K W; Clarkson, T B; Adams, M R et al. (1986) Effects of age and/or puberty on coronary artery atherosclerosis in cynomolgus monkeys. Atherosclerosis 62:137-44 |
